The corner between 53rd and 3rd street in Manhattan
was a well-known spot for male prostitution in New York City, known as The Loop. The Ramones named their second single after it.
The song tells the story of a man who prostitutes himself at the corner.
He is finally picked up, but kills his costumer with a razor blade.
“The song 53rd & 3rd speaks for itself. Everything I write is autobiographical and very real. I can’t write any other way.”
Dee Dee Ramone, The Ramones